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Vandetanib

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Formula: C22H24BrFN4O2
CAS: 443913-73-3
search Element: vandetanib
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Identification

Structural Formula
Vandetanib
CAS:
443913-73-3
EINECS:
Molecular Formula:
C22H24BrFN4O2
MDL:
MFCD07772346
SMILES:
CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
Synonym:
vandetanib(zactima,azd6474) ; vandetanib for research ; vandetanib (zactima) ; vandetanib(zactima),zd6474 ; azd6474 ; zactima ; zd 6474 ; vandetanib base ; vandetanib ; vandetanib, >=98%


Description

Vandetanib is an antagonist of VEGFR (Flk and Flk) and EGFR families. Specifically inhibits kinase activity of Flk-1. Vandetanib is an inhibitor of Flt-4.


Suppliers

Aea.ltd
A70140
+
Shandong SanYoung Industry Co., Ltd
SSI3501400
+
Ambeed, Inc.
A126372
+
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT5102550
+
Shanghai UCHEM Inc.
UCHEM-6931
CSNpharm, Inc.
CSN12186
Wanko Chemical Co., Ltd.
WC240720
Finetech Industry Limited
FIL2501000
+
Carbone Scientific Co., Ltd.
CS280840
+
Pharmacore Co., Limited
PL230690
CM Fine Chemicals
CFC170680
AK Scientific, Inc.
AS190570
+
Xingrui Industry Co., Limited
XIL2901160
+
Capot Chemical Co., Ltd.
22460
+
BOC Sciences
BS120360
+
Amadis Chemical Company Limited
ACCL3101550
+
Leap Chem Co., Ltd
LC180540
+
Santa Cruz Biotechnology, Inc.
220364
Get Quick Quote

CAS equal suppliers

ZD6474
Aea.ltd
A4284
7-((4-aminocyclohexyl)methoxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC443115
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
BLD Pharmatech Ltd
BP1782053460

Prices & Availability




Data is processed


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Properties for Vandetanib

Molecular Weight:
475.35 g·mol−1
Density:
1.406
Melting point:
240-2430C
Boiling point:
488.2-588.2° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol, DMSO (4 mg/ml at 25° C), water (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :
-20°C Freezer
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Alternative Distributors of [Vandetanib]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

YHEDC (Yi Heng Enterprises Development Co.) | Melone Pharmaceutical Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Longschem Co., Ltd. | Nanjing Ange Pharmaceutical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Unispec Chemicals Co. | Shanghai Yingxuan Chempharm Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Apichem Chemical Technology Co., Ltd. | Wuhan Sunrise Technology Development Company Ltd. | Rosewell Industry Co., Ltd. | Suchem Pharma Co., Ltd. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | China ShengDa Pharmaceutical Co., Ltd. | Suzhou Devi Pharma Technology Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | API Vanguard | Watson International Ltd | Cfm Oskar Tropitzsch GmbH | Pharmfar Co., Ltd. | BOC Sciences | All Right Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Agilebiochem Co., Ltd | Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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