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sildenafil

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Formula: C22H30N6O4S
CAS: 139755-83-2
search Element: sildenafil

Identification

Structural Formula
sildenafil
CAS:
139755-83-2
EINECS:
Molecular Formula:
C22H30N6O4S
MDL:
MFCD00867528
SMILES:
CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Synonym:
sildenafil solution ; sildenafil citrate salt ; sildenafil(viagra) ; methanol (test sildenafil, 1.0 mg/ml ) ; 5-[2-ethoxy-5-(4-methylpiperazine-1-sulfonyl)phenyl]-1-methyl-3-propyl-1h,6h,7h-pyrazolo[4,3-d]pyrimidin-7-one ; viagta ; sidanafil ; revatio ; sildenafil ; uk-92480


Description

Sildenafil is a selective inhibitor of PDE5A (the type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.


Suppliers

H&Z Industry Co.,Ltd
HIC200800
Aozeal Certified Standards (AOCS), Inc.
S0005.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
X´ian Taicheng Chem Co., Ltd
XTC2901160
Xiamen Equation Chemical Co.,Ltd
XECC3201600
Daming Changda Co., Ltd.
DC240720
Hangzhou Lingrui Chemical Co., Ltd.
HLC3501400
Pharmacore Co., Limited
PL230690
Hefei Hirisun Pharmatech Co., Ltd
HR130610
AK Scientific, Inc.
AS190570
Xingrui Industry Co., Limited
XIL2901160
Capot Chemical Co., Ltd.
25777
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
338584
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CAS equal suppliers

Sildenafil citrate
Hangzhou Lingrui Chemical Co., Ltd.
HLC12605040
5-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulfonyl)phenyl]-1-methyl-3-N-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidin-7-one
Salsbury Chemicals, Inc.
SC39648118944

Prices & Availability




Data is processed


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Properties for sildenafil

Molecular Weight:
474.58 g·mol−1
Density:
1.40 g/cm3 (Predicted)
Melting point:
187-189 °C
Boiling point:
672.4 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO, methanol, and water (3.5 mg/mL).
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed
Hazard Symbols:
Xi, T, F
Hazard symbol T Hazard symbol F Hazard symbol Xi
Storage temperature :
Refrigerator
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Alternative Distributors of [sildenafil]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Molekula GmbH | Hallochem Pharma Co., Ltd. | Conier Chem & Pharma Ltd | AK Scientific, Inc. | Wuhan Hezhong Biochemical Manufacture Co., Ltd. | Carbone Scientific Co., Ltd. | Jinan Wedo Industrial Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Tianjin Pharmacn Medical Technology Co., Ltd. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | Shanxi Zishan Natural Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Shenzhen Simeiquan Bio-tech Co., Ltd. | Watson International Ltd | BOC Sciences | Sciyu Biotech Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Suzhou Vosun Chemical Co.,Ltd. | Shaanxi TOP Pharm Chemical Co.,Ltd. | Angel Synthesis Co., Ltd | Clearsynth Canada INC. | Hangzhou Dayangchem Co. Ltd. | Wanko Chemical Co., Ltd. | Zhuhai Jiacheng Bio-Tech Co., Ltd. | Haihang Industry Co., Ltd.

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