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L-Selenomethionine

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Formula: C5H11NO2Se
CAS: 3211-76-5
search Element: selenomethionine
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Identification

Structural Formula
L-Selenomethionine
CAS:
3211-76-5
EINECS:
Molecular Formula:
C5H11NO2Se
MDL:
MFCD00037210
SMILES:
C[Se]CC[C@@H](C(=O)O)N
Synonym:
seleno-l-methionine ; l-seleno-l-methionine ; l-selenomethionine ; the l-selenomethionine ; thallium ethylsufate ; l-selenomethionine 0.5% ; l-(+)-selenomethionine ; semet ; l-selenomethinonine ; l-selenomethionine usp


Description

L-Selenomethionine displays antioxidant activity and has been shown to increase the activity of glutathione peroxidase in endothelial cells. Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks, mutations and interference with protein tyrosine-based signaling and other protein functions due to formation of 3-nitrotyrosine, caused by excessive peroxynitrite. L-Selenomethionine administration to cancer cell lines (MCF-7/S breast carcinoma, DU-145 prostate cancer cells and UACC-375 melanoma) results in apoptotic cell death and aberrant mitosis. These human tumor cell lines exhibited dose-dependent growth inhibition by L-Selenomethionine in the micromolar range (45 to 130 μM), while growth inhibition of normal fibroblasts required 1 mM L-Selenomethionine.


Suppliers

Shandong Ench Chemical Co.,Ltd
SECC5402700
+
Lori Industry Co., Ltd
LI3961188
+
H&Z Industry Co.,Ltd
HIC3601440
+
Minascent Technologies GmbH
MT4861458
+
Shandong SanYoung Industry Co., Ltd
SSI6302520
+
Ambeed, Inc.
A355129
+
Indofine Chemical Co, Inc.
06-1368
AIDP, Inc.
A180360
Alpha Biopharmaceuticals Co., Ltd.
AB6121836
+
Hangzhou Verychem Science & Technology Co., Ltd.
HVST8644320
+
CSNpharm, Inc.
CSN23416
scienTEST - bioKEMIX GmbH
S-B4501800
+
CM Fine Chemicals
CFC3061224
Xingrui Industry Co., Limited
XIL5222088
+
Santa Cruz Biotechnology, Inc.
204050
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Prices & Availability




Data is processed


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Properties for L-Selenomethionine

Molecular Weight:
196.11 g·mol−1
Melting point:
265 °C
Boiling point:
320.78° C at 760 mmHg (Predicted)
Solubility:
H2O: 50 mg/mL
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2
GHS09

GHS09
Environmental hazard
  • Acute hazards to the aquatic environment, category 1
  • Chronic hazards to the aquatic environment, categories 1, 2
  • Environmental toxicity, categories 1, 2

Safety & Transport Information

Risk Codes:
R23/25 - Toxic by inhalation and if swallowed
R33 - Danger of cumulative effects
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S20/21 - When using do not eat, drink or smoke
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
T, N
Hazard symbol T Hazard symbol N
Storage temperature :
-20°C
RID/ADR certification :
UN 3283 6.1 / PG 2
x

Alternative Distributors of [L-Selenomethionine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Sabinsa Corporation | Chem-Impex International, Inc. | CCS. CHEM. Co., Ltd. | ABCR GmbH & Co. KG | TCI Europe NV | Suzhou Rovathin Pharmatech Co., Ltd | East Chemical Industry Co., Ltd. | Scandinavian Formulas, Inc. | Clearsynth Canada INC.

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