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Riluzole

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Formula: C8H5F3N2OS
CAS: 1744-22-5
search Element: riluzole
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Identification

Structural Formula
Riluzole
CAS:
1744-22-5
EINECS:
Molecular Formula:
C8H5F3N2OS
MDL:
MFCD00210213
SMILES:
C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
Synonym:
riluzole ; rilutek ; pk 26124 ; rp-54274 ; riluzole(rilutek) ; rilutek (tn) ; riluzole (200 mg) ; bf-37 ; prestwick-03a08 ; buttpark 13\02-09


Description

Riluzole is a sodium channel protein inhibitor and potent neuroprotective agent. It has been shown to preferentially block tetrodotoxin-sensitive sodium channels, which are associated with damaged neurons. In the presence of negative potentials, Riluzole was shown to also block tetrodotoxin-resistant sodium channels. It has been reported that Riluzole exerts its neuroprotective action under ischemic conditions, thereby suppressing glutamatergic receptor stimulation and calcium influx. Research shows that this product activates the TREK family of potassium channels and directly affects the glutamatergic system.
Riluzole inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Riluzole blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes.


Suppliers

Aozeal Certified Standards (AOCS), Inc.
R0037.00
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI5522208
+
European Technologies Inc.
ET208624
Xiamen Equation Chemical Co.,Ltd
XECC2561280
+
CSNpharm, Inc.
CSN12584
Xingrui Industry Co., Limited
XIL232928
+
Leap Chem Co., Ltd
LC144432
+
Santa Cruz Biotechnology, Inc.
201081
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Prices & Availability




Data is processed


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Properties for Riluzole

Molecular Weight:
234.2 g·mol−1
Density:
1.6 g/cm3 (Predicted)
Melting point:
116-118 °C
Boiling point:
296.3±50.0° C at 760 mmHg
Solubility:
DMSO: ≥25 mg/mL
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
Safety Codes:
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
irritant
Hazard Symbols:
T, Xi
Hazard symbol T Hazard symbol Xi
Storage temperature :
Store at RT
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Riluzole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Hefei Photochem Trading Co., Ltd | Wuxi Mizat Chemical Technology Co., Ltd. | Jinan Great Chemical Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Watson International Ltd | 3B Scientific Corporation | Hangzhou Onicon Chemical Co., Ltd. | Auspure Biotechnology Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Qichun QiLong Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Clearsynth Canada INC. | Shanghai AOKChem Group Limited | Melone Pharmaceutical Co., Ltd. | Jinan Wedo Industrial Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Haihang Industry Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | AOKBIO Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Wanko Chemical Co., Ltd.

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