Element:
Identification
Molecular Formula:
C2 2 H2 0 N4 O
SMILES:
NC1=CC2=C(C=C1)N=CN=C2NCCC1=CC=C(OC2=CC=CC=C2)C=C1
Synonym:
4,6-quinazolinediamine, n4-[2-(4-phenoxyphenyl)ethyl]- ; evp-4593 ; evp 4593 ; n4-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine ; 4-n-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine ; evp4593 ; qnz ; qnz (evp4593)
Description
QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling. Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection. Research results suggest that QNZ fully blocks the increase in K currents in rat sensory neurons. QNZ has been used to study colorectal cancer and Schwann cell functioning.
Suppliers
Pharmacore Co., Limited
PL69207
Santa Cruz Biotechnology, Inc.
200675
CAS equal suppliers
N4-(4-phenoxyphenethyl)quinazoline-4,6-diamine
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Hangzhou J&H Chemical Co., Ltd.
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6-Amino-4-(4-phenoxyphenylethylamino)quinazoline
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6-Amino-4-(4-phenoxyphenylethylamino)quinazoline
Amadis Chemical Company Limited
ACCL595229760
N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine
Leap Chem Co., Ltd
LC655219656
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
Downloads
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Properties for QNZ
Molecular Weight:
356.42 g·mol−1
Melting point:
169-175 °C
Boiling point:
602.00° C at 760 mmHg
Solubility:
Soluble in DMSO (20 mg/ml), DMF (30 mg/ml), ethanol (10 mg/ml), and 1:1 solution DMF:PBS(pH 7.2) (0.5 mg/ml).
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Safety & Transport Information
Storage temperature :
Refrigerator, Under Inert Atmosphere
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Alternative Distributors of [QNZ]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.
Element: 
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