MMP-3 Inhibitor V | CAS 185672-77-9

Element: inhibitor

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C-S » Chemicals » mmp-inhibitor-PX85637

Identification

MMP-3 Inhibitor V

CAS:

185672-77-9

EINECS:

Molecular Formula:

C₁₆H₁₃NO₄

MDL:

MFCD04974536

SMILES:

C1=CC=C2C(=C1)C3=C(O2)C=CC(=C3)/C(=NO)/CCC(=O)O

Synonym:

mmp-3 inhibitor v ; 4-dibenzofuran-2'-yl-4-hydroximino-butyric acid

Description

MMP-3 Inhibitor V is a potent and competitive inhibitor of both human and rabbit MMP-3 catalytic domains (wild type and mutants) with K_i values in the low μM range. It is shown that the functional groups, namely the oxime and the carboxyl, interact with the zinc active site.