Letrozole | CAS 112809-51-5 | Chemical-Suppliers

Element: letrozole

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C-S » Chemicals » letrozole-PX72649

Identification

Letrozole

CAS:

112809-51-5

EINECS:

Molecular Formula:

C₁₇H₁₁N₅

MDL:

MFCD00866241

SMILES:

C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3

Synonym:

letroz ; cgs-20267 ; lelrozol ; femara ; lerozole ; letrozole ; letrozolex ; letrozole99% ; letrazole ; letrozol

Description

Letrozole acts as a nonsteroidal CYP19 (aromatase) inhibitor. It is also known to inhibit estradiol production in vitro in hamster ovarian tissue that is LH-stimulated. Letrozole has not been shown to have a significant effect on progesterone production up to 350 M. Letrazole has been shown to inhibit aldosterone production in vitro in rat adrenal tissue stimulated by ACTH. No significant effect has been seen on corticosterone production at 350 M. Letrozole has no effect on corticosterone or aldoterone levels in vivo in ACTH-treated rats.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

Shandong Minglang Chemical Co., Ltd

SMC3151260

H&Z Industry Co.,Ltd

HIC180720

Wuhan PharmChem Co., LTD.

WP225675

Aea.ltd

A63126

Shandong SanYoung Industry Co., Ltd

SSI3151260

Arcadia Biotechnology

AB189567

Shanghai Worldyang Chemical Co., Ltd.

SWC3331332

Sancai Industry Co.,Ltd.

SIC216864

Daming Changda Co., Ltd.

LLB00232

Hangzhou Keying Chem Co., Ltd.

HKC2701080

Hangzhou Lingrui Chemical Co., Ltd.

HLC3151260

Sigma-Aldrich International GmbH

SI288864

scienTEST - bioKEMIX GmbH

S-B225900

Carbone Scientific Co., Ltd.

CS252756

AK Scientific, Inc.

AS171513

Amadis Chemical Company Limited

ACCL2791395

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

204791

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CAS equal suppliers

Letrozol

Simagchem Corporation

SC168504

Letrozol

Xiamen Equation Chemical Co.,Ltd

XECC2561280

Letrozol

Arakato Development Ltd

AD184552

Letrozol

Nantong Xindao Biotech Ltd

NXB208832

4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-benzonitrile

Hangzhou J&H Chemical Co., Ltd.

HJC821532860

Benzonitrile, 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-

Angene International Limited

AGN-PC-04XZ2M

4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile

Manchester Organics Limited

U35944

Prices & Availability

Data is processed

Properties for Letrozole

Molecular Weight:

285.3 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

181-183 °C

Boiling point:

~563.5° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (<1 mg/ml at 25° C), DMSO (57 mg/ml at 25° C), ethanol (<5 mg/ml, partially ), chloroform, and methanol.

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Letrozole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified