IKK 16 | CAS 1186195-62-9 | Chemical-Suppliers

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C-S » Chemicals » ikk-PX78546

Identification

IKK 16

CAS:

1186195-62-9

EINECS:

Molecular Formula:

C₂₈H₂₉N₅OS.HCl

MDL:

MFCD09971091

SMILES:

C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5.Cl

Synonym:

Description

IKK 16 is a selective IκB kinase (IKK) inhibitor (IC₅₀ values are 40, 70 and 200 nM for IKK-2, IKK complex and IKK-1 respectively). This compound inhibits TNF-α-stimulated IκB degradation and expression of adhesion molecules E-selectin, ICAM and VCAM (IC₅₀ values are 1.0, 0.5, 0.3 μM respectively).

Suppliers

Santa Cruz Biotechnology, Inc.

204009

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CAS equal suppliers

IKK-16

Hangzhou Lingrui Chemical Co., Ltd.

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Ikk-16 hydrochloride

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Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

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[4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone hydrochloride (1:1)

Leap Chem Co., Ltd

LC2948488452

Prices & Availability

Data is processed

Properties for IKK 16

Molecular Weight:

520.09 g·mol−1

Boiling point:

737.8° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (50 mM), and DMSO (100 mM).

Safety & Transport Information

coming up soon

Alternative Distributors of [IKK 16]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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