Guanidine Hydrochloride | CAS 50-01-1

Element: hydrochloride guanidine

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C-S » Chemicals » guanidine-hydrochloride-PX65742

Identification

Guanidine Hydrochloride

CAS:

50-01-1

EINECS:

200-002-3

Molecular Formula:

CH₅N₃.HCl

MDL:

MFCD00013026

SMILES:

C(=N)(N)N.Cl

Synonym:

guanidium chloride ; gdmcl ; guanidinium chloride ; guanidine hci ; aminoformamidine hcl ; guhy ; usafek-749 ; guanidine hydr ; guanidinechloride ; guanidine hcl

Description

Guanidine Hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. Guanidine Hydrochloride is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins and isolation of RNA. At higher concentrations, this strong denaturant has been reported to solubilize denatured insoluble proteins such as inclusion bodies. When utilized at lower concentrations, Guanidine Hydrochloride is noted to be useful in prompting the refolding of denatured proteins. Guanidine Hydrochloride is also been reported to allow return of enzymatic activity in protocols using Guanidine Hydrochloride as a first step. Guanidine Hydrochloride is an inhibitor of RNase.

Suppliers

XD BIOCHEMS Ltd

XB6902070

Krada CPS Industry S.L

KCIS10125060

Fountain Biotechnology Co.,Ltd

FBC13805520

Shandong Ench Chemical Co.,Ltd

SECC13806900

OPQ Chemical Co., Ltd

OC9662898

Wuhan PharmChem Co., LTD.

WP11503450

Yixing TRY New Materials Co.,Ltd.

YTNMC15189108

Shandong Minglang Chemical Co., Ltd

SMC16106440

Shandong SanYoung Industry Co., Ltd

SSI16106440

Lori Industry Co., Ltd

LI10123036

Nantong Xindao Biotech Ltd

NXB11964784

Refine Chemical Co.,Ltd.

RCC11044416

Create Chemical Co., Ltd.

CC11503450

BLD Pharmatech Ltd

BP8282484

Shandong Lanhai Industry Co.,Ltd.

SLIC15187590

H&Z Industry Co.,Ltd

HIC9203680

Biovectra Dcl

BD5981794

Doe & Ingalls, Inc.

DI8742622

Amresco Inc.

A5521104

Indofine Chemical Co, Inc.

Bio-192

VWR International, LLC ( United Biochemicals )

29110-KI

Henan Haofei Chemical Co.,Ltd

HHCC13346670

Fabrichem, Inc.

F6901380

Alzchem Trostberg GmbH

AT10123036

Evonik Industries AG

EIA9203680

X´ian Taicheng Chem Co., Ltd

XTC13345336

Hangzhou Verychem Science & Technology Co., Ltd.

HVST220811040

Shanghai Yayu Biomedical Co., Ltd

SYB15186072

Shanghai Mintchem Development Co., Ltd.

SMD17947176

Shanghai Worldyang Chemical Co., Ltd.

SWC17026808

Xiamen Equation Chemical Co.,Ltd

XECC14727360

Hangzhou Zhongqi Chem Co., Ltd

HZC13805520

Sancai Industry Co.,Ltd.

SIC11044416

Hainan Zhongxin Chemical Co., Ltd.

HZC15646256

Daming Changda Co., Ltd.

LLB00634

Aecochem Corp.

AC6441932

Hangzhou Keying Chem Co., Ltd.

HKC13805520

Hangzhou Lingrui Chemical Co., Ltd.

HLC16106440

scienTEST - bioKEMIX GmbH

S-B11504600

Finetech Industry Limited

FIL11504600

Xiamen Hisunny Chemical Co., Ltd.

XHC15186072

AK Scientific, Inc.

AS8742622

Xiamen Kinbester Co., Ltd.

XK11963588

Simagchem Corporation

SC9662898

Xingrui Industry Co., Limited

XIL13345336

Zehao Industry Co., Ltd.

ZI11043312

Leap Chem Co., Ltd

LC8282484

Santa Cruz Biotechnology, Inc.

202637

Dayang Chem (Hangzhou) Co.,Ltd.

DC14265704

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Serva Electrophoresis GmbH

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35776529

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G9015-15

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TCI Chemicals (India) Pvt. Ltd.

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Prices & Availability

Data is processed

Properties for Guanidine Hydrochloride

Molecular Weight:

95.53 g·mol−1

Density:

1.18 g/mL at 25 °C(lit.)

Melting point:

180-185 °C(lit.)

Solubility:

H₂O: 6 M, clear, colorless

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Xn, Xi

Storage temperature :

Store at RT.

Alternative Distributors of [Guanidine Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

-/-

MSDS:

-/-

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