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Ginkgolide B

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Formula: C20H24O10
CAS: 15291-77-7
search Element: ginkgolide

Identification

Structural Formula
Ginkgolide B
CAS:
15291-77-7
EINECS:
Molecular Formula:
C20H24O10
MDL:
MFCD05662347
SMILES:
CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O
Synonym:
ginkgolidea,1-hydroxy-, (1β)- ; ginkgolide b from ginkgo leaves ; ginkgolide b ; (1r,3s,3as,4r,6ar,7ar,7br,8s,10as,11r,11ar)-3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9h-1,7a-(epoxymethano)-1h,6ah-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4h)-trione ; 7-deoxyginkgolide c ; ginkgolide b from ginkgo biloba leaves ; bginkgolid ; ginkgolide b(sh) ; ginkgolide b, from ginkgo biloba ; bn 52021


Description

Ginkgolide B (BN 52021), originally extracted from Ginkgo biloba leaves, is the most potent member of the ginkgolide family of PAF-R (platelet-activating factor receptor) antagonists. PAF is an important mediator of many biological processes including cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation. Mechanistic studies suggest that Ginkgolide B speeds up PAF hydrolysis by promoting PAF-AH I α2 homodimer activity. Additionally, this compound has been reported to inhibit neutrophil degranulation in vitro.


Suppliers

Chengdu Pufeide Biotech. Co., Ltd
CPB7923168
H&Z Industry Co.,Ltd
HIC4801920
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI16566624
Indofine Chemical Co, Inc.
028822
Xiamen Equation Chemical Co.,Ltd
XECC7683840
CSNpharm, Inc.
CSN12569
Sigma-Aldrich International GmbH
SI7682304
Carbone Scientific Co., Ltd.
CS6722016
Pharmacore Co., Limited
PL5521656
Acinopeptide Co., Ltd.
A5281056
Simagchem Corporation
SC5041512
Xingrui Industry Co., Limited
XIL6962784
BOC Sciences
BS288864
Leap Chem Co., Ltd
LC4321296
Santa Cruz Biotechnology, Inc.
201037
Dayang Chem (Hangzhou) Co.,Ltd.
DC7442976
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Properties for Ginkgolide B

Molecular Weight:
424.4 g·mol−1
Density:
~1.6 g/cm3 (Predicted)
Melting point:
280 °C (dec.)
Boiling point:
~762.4° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (100 mM), ethanol (25 mM), acetone, ethyl acetate, dioxane, methanol, and water (partly miscible).
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Safety & Transport Information

Storage temperature :
2-8°C
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Alternative Distributors of [Ginkgolide B]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | BOC Sciences | ABCR GmbH & Co. KG | Jinan Great Chemical Co., Ltd. | BioBioPha Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Shanghai Tauto Biotech Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Carl Roth GmbH + Co KG | Chengdu Biopurify Phytochemicals Ltd. | Shanghai AOKChem Group Limited | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai Brightol International Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | Suzhou Bichal Biological Technology Co., Ltd.

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