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8(S),15(S)-DiHETE (Z, E, Z, E)

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Formula: C20H32O4
CAS: 80234-65-7
search Element: dihete

Identification

Structural Formula
8(S),15(S)-DiHETE (Z, E, Z, E)
CAS:
80234-65-7
EINECS:
Molecular Formula:
C20H32O4
MDL:
SMILES:
CCCCC[C@@H](/C=C/C=CC=C[C@H](C/C=CCCCC(=O)O)O)O
Synonym:
(8s,15s)-dihete ; 8(s),15(s)-dihydroxyeicosa-5z,9e,11z,13e-tetraenoic acid ; (8s,15s)-dihydroxy-(5z,9e,11z,13e)-eicos atetraenoi ; 8(s),15(s)-dihete (z, e, z, e) ; (8s,15s)-dihydroxy-(5z,9e,11z,13e)-eicosatetraenoic acid ; (8s,15s)-dihydroxy-(5z,9e,11z,13e)-*eicosatetraen


Description

8(S),15(S)-DiHETE (Z, E, Z, E) is a novel dioxygenation product of arachidonic acid which possesses chemotactic activity for human polymorphonuclear leukocytes (PMNLs) comparable to that of leukotriene B4. Studies show that (8S,15S)-diHETE from PMNLs, keratinocytes, and other epithelial cells may modulate normal primary afferent function and contribute to inflammatory hyperalgesia. Studies show that 8(S)-15(S)-diHETE antagonizes the hyperalgesic activity of its stereoisomer 8(R)-15(S)-diHETE but does not suppress PGE-2 induced hyperalgesia.


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Santa Cruz Biotechnology, Inc.
200415
Santa Cruz Biotechnology, Inc.
sc-200415
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Properties for 8(S),15(S)-DiHETE (Z, E, Z, E)

Molecular Weight:
336.47 g·mol−1
Boiling point:
78° C
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
F, Xi
Hazard symbol F Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1170 3 / PG 2
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Alternative Distributors of [8(S),15(S)-DiHETE (Z, E, Z, E)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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