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N,O-Didesmethyl-(rac-venlafaxine) Glucuronide Hydrochloride

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Formula: C21H32ClNO8
CAS: 1021933-99-2

Identification

Structural Formula
N,O-Didesmethyl-(rac-venlafaxine) Glucuronide Hydrochloride
CAS:
1021933-99-2
EINECS:
Molecular Formula:
C21H32ClNO8
MDL:
SMILES:
Cl.CNC[C@H](C1=CC=C(O[C@@H]2OC([C@@H](O)C(O)C2O)C(O)=O)C=C1)C1(O)CCCCC1
Synonym:


Description

N,O-Didesmethyl-(rac-venlafaxine) Glucuronide Hydrochloride is a metabolite of Venlafaxine. Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.


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Santa Cruz Biotechnology, Inc.
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Properties for N,O-Didesmethyl-(rac-venlafaxine) Glucuronide Hydrochloride

Molecular Weight:
461.93 g·mol−1
Melting point:
>180°C (lit.)(dec.)
Solubility:
Soluble in DMSO, and water.
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Alternative Distributors of [N,O-Didesmethyl-(rac-venlafaxine) Glucuronide Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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Mol File:
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MSDS:
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