Cyclosporin H | CAS 83602-39-5 | Chemical-Suppliers

Element: cyclosporin

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C-S » Chemicals » cyclosporin-PX80498

Identification

Cyclosporin H

CAS:

83602-39-5

EINECS:

Molecular Formula:

C₆₂H₁₁₁N₁₁O₁₂

MDL:

MFCD04039488

SMILES:

CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

Synonym:

cyclosporin h, >=95% ; cyclosporine impurity-h ; 5-(n-methyl-d-valine)cyclosporin a ; 5-(n-methyl-d-valine)cyclosporine a ; sandoz 37-839 ; cyclo[l-alanyl-d-alanyl-n-methyl-l-leucyl-n-methyl-l-leucyl-n-methyl-d-valyl-3-hydroxy-n,4-dimethyl-l-2-amino-6-octenoyl-l-2-aminobutanoyl-n-methylglycyl-n-methyl-l-leucyl-l-valyl-n-methyl-l-leucyl] ; cyclosporin h ; cyclosporin h, from micromonospora ; cyclo[l-alanyl-d-alanyl-n-methyl-l- leucyl-n-methyl-l-leucyl-n-methyl-d-valyl-(3r,4r,6e)-6,7-didehydro-3-hydroxy-n,4-dimethyl-l-2-aminooctanoyl-l-2-aminobutanoyl-n-methylglycyl-n-methyl-l-leucyl-l-valyl-n-methyl-l-leucyl]

Description

Cyclosporin H is immunologically inactive and does not bind to immunophilin. Cyclosporin H is a potent inhibitor of tumor promoting phorbol ester TPA/PMA in mouse skin cells. It also acts as a potent inhibitor of Ca²⁺/calmodulin-dependent EF-2 phosphorylation in vitro. Cyclosporin H is a potent and selective antagonist of formyl peptide receptor (FPR), which thereby inhibits formyl peptide-induced superoxide formation.

Suppliers

Aea.ltd

A182364

Indofine Chemical Co, Inc.

06-464

Alpha Biopharmaceuticals Co., Ltd.

AB8842652

Xiamen Equation Chemical Co.,Ltd

XECC8324160

Pharmacore Co., Limited

PL5981794

Iris Biotech GmbH

LS-1073

Simagchem Corporation

SC5461638

BOC Sciences

BS312936

Amadis Chemical Company Limited

ACCL8064030

Leap Chem Co., Ltd

LC4681404

Santa Cruz Biotechnology, Inc.

203013

Dayang Chem (Hangzhou) Co.,Ltd.

DC8063224

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CAS equal suppliers

Cyclosporine H

Aozeal Certified Standards (AOCS), Inc.

C0009.05

Prices & Availability

Data is processed

Properties for Cyclosporin H

Molecular Weight:

1202.61 g·mol−1

Density:

~1.0 g/cm³ (Predicted)

Melting point:

148-151 °C

Boiling point:

~1293.8° C at 760 mmHg (Predicted)

Solubility:

Soluble in 100% ethanol, acetone, ethyl acetate, and chloroform. Insoluble in water.

Safety & Transport Information

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Cyclosporin H]

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