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CAY10505

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Formula: C14H8FNO3S
CAS: 1218777-13-9
search Element: cay10505
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Identification

Structural Formula
CAY10505
CAS:
1218777-13-9
EINECS:
Molecular Formula:
C14H8FNO3S
MDL:
SMILES:
C1=CC(=CC=C1C2=CC=C(O2)/C=C/3C(=O)NC(=O)S3)F
Synonym:


Description

CAY10505 is a potent PI3Kγ inhibitor with an IC50 of 30 nM. CAY10505 also prevents other α, β, and δ isoforms with IC50 values of 0.94, 20, and 20 μM, respectively. CAY10505 also inhibits casein kinase 2 (CK2, IC50 = 20 nM). CAY10505 suppresses the phosphorylation of the PI3K substrate PKB/Akt in murine macrophages (IC50 = 228 nM).


Suppliers

Amadis Chemical Company Limited
ACCL2481240
+
Santa Cruz Biotechnology, Inc.
364456
Dayang Chem (Hangzhou) Co.,Ltd.
DC248992
+
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Prices & Availability




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Properties for CAY10505

Molecular Weight:
289.28 g·mol−1
Density:
~1.5 g/cm3 (Predicted)
Melting point:
240.05 °C (Predicted)
Boiling point:
558.78 °C at 760 mmHg (Predicted)
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Safety & Transport Information

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Alternative Distributors of [CAY10505]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ShangHai Biochempartner Co., Ltd. | Shanghai Sun-shine Chemical Technology Co., Ltd. | BOC Sciences

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