Canertinib | CAS 267243-28-7 | Chemical-Suppliers

Element: canertinib

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C-S » Chemicals » canertinib-PX75179

Identification

Canertinib

CAS:

267243-28-7

EINECS:

Molecular Formula:

C₂₄H₂₅ClFN₅O₃

MDL:

MFCD09837878

SMILES:

C=CC(=O)Nc1cc2c(ncnc2cc1OCCCN1CCOCC1)Nc1ccc(F)c(Cl)c1

Synonym:

2-propenamide,n-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]- ; ci-1033(canertinib) ; canetinib ; n-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide ; pd-183805 ; n-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide ; canertinib (ci-1033) ; n-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-en ; canertinib base ; n-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]acrylamide ; canertinib--ci-1033, pd-183805 ; cl 1033 ; n-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide ; 4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propyloxy]-6-[(vinylcarbonyl)amino]quinazoline

Description

Canertinib is a potent and selective inhibitor of tyrosine residue phosphorylation of EGFR, blocking signal transgression and ceasing angiogenisis. Canertinib displays an IC₅₀ = 1.5nM. Additionally, Canertinib's action in inhibiting EGFR increases apoptosis in cancerous cell lines in a titratable fashion.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

Aea.ltd

A70140

Shandong SanYoung Industry Co., Ltd

SSI3501400

CSNpharm, Inc.

CSN12261

Capot Chemical Co., Ltd.

22407

Amadis Chemical Company Limited

ACCL3101550

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

207397

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CAS equal suppliers

CI1033

Aea.ltd

A4284

CI-1033

ShangHai Biochempartner Co., Ltd.

BCP01790

Caneritinib; CI-1033

Excenen Pharmatech Co., Ltd.

EX-A078

N-(4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC116239

N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide

Xingrui Industry Co., Limited

XIL38976155904

Prices & Availability

Data is processed

Properties for Canertinib

Molecular Weight:

485.944 g·mol−1

Density:

1.355 g/cm3

Melting point:

175-180° C

Boiling point:

691 °C at 760 mmHg

Flash point:

371.7 °C

Solubility:

Soluble in DMSO (2 mg/ml), methanol, ethanol (9 mg/ml), and water (<1 mg/ml).

Physical Description:

white or similar to white crystalline powder

Safety & Transport Information

coming up soon

Alternative Distributors of [Canertinib]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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Canertinib HCl

Canertinib Dihydrochloride

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