Benzamide | CAS 55-21-0 | Chemical-Suppliers

Element: benzamide

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C-S » Chemicals » benzamide-PX69561

Identification

Benzamide

CAS:

55-21-0

EINECS:

200-227-7

Molecular Formula:

C₇H₇NO

MDL:

MFCD00007968

SMILES:

C1=CC=C(C=C1)C(=O)N

Synonym:

Description

Benzamide is the amide derivative of benzoic acid and an inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Benzamide mimics the structure of the nicotinamide portion of the coenzyme NAD⁺, blocking the function of ADP-ribose transfer from NAD⁺ to target histone proteins performed by PARP and impeding formation of the poly(ADP-ribose) polymer. PARP activation in response to DNA strand breaks can lead to deleterious depletion of cellular NAD⁺, and Benzamide was shown to block NMDA- and NO-mediated neurotoxicity in rat brain through PARP inhibition. Benzamide is further demonstrated to partially prevent decreases in striatal levels of NAD⁺ and ATP produced by neurotoxic amounts of kainic acid.

Suppliers

Ambeed, Inc.

A446394

Krada CPS Industry S.L

KCIS198990

Shandong SanYoung Industry Co., Ltd

SSI3151260

BLD Pharmatech Ltd

BP162486

ICC Industries B.V

IIB162648

Xiamen Equation Chemical Co.,Ltd

XECC2881440

Hangzhou Zhongqi Chem Co., Ltd

HZC2701080

Aecochem Corp.

AC126378

CSNpharm, Inc.

CSN10401

Merck Schuchardt OHG

MSO180720

Hangzhou Keying Chem Co., Ltd.

HKC2701080

scienTEST - bioKEMIX GmbH

S-B225900

Xiamen Hisunny Chemical Co., Ltd.

XHC2971188

AK Scientific, Inc.

AS171513

Simagchem Corporation

SC189567

Xingrui Industry Co., Limited

XIL2611044

Amadis Chemical Company Limited

ACCL2791395

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

202494

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CAS equal suppliers

Benzamide 99%

Acros Organics BVBA

AOB247988

Benzamide, 98+%

Alfa (A Johnson Matthey Company)

A4801440

Cefaclor Impurity I

Aozeal Certified Standards (AOCS), Inc.

C0099.08

Benzamide Zone Refined (number of passes:20)

TCI Chemicals (India) Pvt. Ltd.

B0220

Prices & Availability

Data is processed

Properties for Benzamide

Molecular Weight:

121.14 g·mol−1

Density:

1.34 g/cm³ at 20° C

Melting point:

125-128° C (lit.)

Boiling point:

288° C at 760 mmHg

Solubility:

Soluble in water (13.5 mg/ml at 25° C), methanol (almost transparency), pyridine (303.03 mg/ml), ethanol (166.67 mg/ml), and ethyl ether (slightly).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Alternative Distributors of [Benzamide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified