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BCTC

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Formula: C20H25ClN4O
CAS: 393514-24-4
search Element: bctc

Identification

Structural Formula
BCTC
CAS:
393514-24-4
EINECS:
Molecular Formula:
C20H25ClN4O
MDL:
MFCD08690556
SMILES:
CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl
Synonym:
1-Piperazinecarboxamide, 4-(3-chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-


Description

BTBC is an effective and potent transient receptor potential VR1 (vanilloid-1, TRPV1) channel antagonist. VR1 (TRPV1) is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat. Studies show that BTBC and Capsazepine both inhibit the activation of rat VR1 (vanilloid receptor 1), induced with acid or Capsaicin. Other VR1 (TRPV1) antagonists include AMG9810 (sc-201477) and SB705498. BCTC is an inhibitor of ANKTM1 and TRPM8.


Suppliers

Santa Cruz Biotechnology, Inc.
205599
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CAS equal suppliers

4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
Leap Chem Co., Ltd
LC1296038880
4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
Finipharma Ltd
F1008020160

Prices & Availability




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Properties for BCTC

Molecular Weight:
372.9 g·mol−1
Density:
~1.23 g/cm3 (Predicted)
Melting point:
150-152° C
Boiling point:
~561.58° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (20 mg/ml), ethanol (15 mg/ml with warming), and DMF.
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Safety & Transport Information

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Alternative Distributors of [BCTC]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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