K-252b | CAS 99570-78-2 | Chemical-Suppliers

Element: 252b

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C-S » Chemicals » -PX65365

Identification

K-252b

CAS:

99570-78-2

EINECS:

Molecular Formula:

C₂₆H₁₉N₃O₅

MDL:

MFCD09878299

SMILES:

CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O

Synonym:

antibiotic k 252b ; k-252b, nocardiopsis sp ; (9r,10s,12s)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid ; k252b ready made ; protein kinase inhibitor k-252b ; k-252b, nocardiopsis species ; 9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, (9s,10r,12r)- ; kt 5556 ; 9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, [9s-(9a,10b,12a)]- ; k 252b ; k-252b solution ; k252b antibiotic k 252b kt 5556 ; k-252b

Description

K-252b is a general, cell permeable protein kinase inhibitor which acts by binding to the ATP binding domain of the kinase. K-252b is a potent inhibitor of CaMKII (Ca²⁺/calmodulin kinase II), MYLK (myosin light chain kinase, K_i=0.147 μM), PKA (cAMP- dependent protein kinase, K_i=0.09 μM), PKC (protein kinase C, K_i=0.02 μM), and cGKI (cGMP-dependent protein kinase, K_i=0.1 μM).

Suppliers

Iris Biotech GmbH

LS-1035

Santa Cruz Biotechnology, Inc.

200585

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CAS equal suppliers

K252b

Santa Cruz Biotechnology, Inc.

SCB3001200

K252b

Fermentek Ltd.

K252b

Antibiotic K 252b

Leap Chem Co., Ltd

LC9182754

9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, (9S,10R,12R)-

Salsbury Chemicals, Inc.

SC66504199512

Prices & Availability

Data is processed

Properties for K-252b

Molecular Weight:

453.452 g·mol−1

Density:

1.78 g/cm³ (Predicted)

Melting point:

318.16° C (Predicted)

Boiling point:

769.82° C at 760 mmHg (Predicted)

Safety & Transport Information

Hazard Symbols:

Storage temperature :

-20°C

Alternative Distributors of [K-252b]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | Fermentek Ltd. | Jinan Haohua Industry Co., Ltd.

Downloads

Mol File:

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MSDS:

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