AS-605240 | CAS 648450-29-7 | Chemical-Suppliers

Element: 605240

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C-S » Chemicals » -PX61092

Identification

AS-605240

CAS:

648450-29-7

EINECS:

Molecular Formula:

C₁₂H₇N₃O₂S

MDL:

MFCD11100415

SMILES:

C1=CC2=NC=CN=C2C=C1/C=C3/C(=O)NC(=O)S3

Synonym:

(z)-5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione ; as-605240, >=98% ; 2,4-thiazolidinedione, 5-(6-quinoxalinylmethylene)- ; as605240 ; as-605240 5-(6-quinoxalinylmethylene)-2,4-thiazolidinedione ; pi 3-kinase inhibitor (as605240) b-0301 ; as-605240(as 605240) ; as 605240 ; 5-(6-quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione ; 5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione ; 5-(6-quinoxalinylmethylene)-2,4-thiazolidinedione ; (e)-5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione

Description

AS-605240 is a potent, cell permeable and ATP-competitive inhibitor of PI 3-kinase p110 γ (PI 3-kinase γ) (IC₅₀ = 8 nM). AS-605240 also exhibits selectivity over other PI 3-kinase isoforms. This compound supresses the progress of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. AS-605240 is an inhibitor of PI 3-kinase p110 α, PI 3-kinase p110 β and PI 3-kinase p110 δ.

Suppliers

Ambeed, Inc.

A108127

CSNpharm, Inc.

CSN13098

Pharmacore Co., Limited

PL207621

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

221272

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CAS equal suppliers

AS605240

Excenen Pharmatech Co., Ltd.

EX-A026

AS 605240

Santa Cruz Biotechnology, Inc.

SCB2701080

AS 605240

Shandong Ench Chemical Co.,Ltd

SECC2701350

AS 605240

Aea.ltd

A63126

PI 3-Kgamma Inhibitor

Santa Cruz Biotechnology, Inc.

sc-203191

PI 3-Kγ Inhibitor

Santa Cruz Biotechnology, Inc.

203191

5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione

Chemieliva Pharmaceutical Co., Ltd.

CP686020580

2,4-Thiazolidinedione, 5-(6-quinoxalinylmethylene)-

Angene International Limited

AGN-PC-04TNQO

Prices & Availability

Data is processed

Properties for AS-605240

Molecular Weight:

257.2679 g·mol−1

Density:

1.553 g/cm3

Melting point:

243.03° C (Predicted)

Boiling point:

565.14° C (Predicted)

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [AS-605240]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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